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Bacillus coagulans GBI-30 6086

◑ Environmental
Sequenced
Public genome assembly available

Bacillus coagulans GBI-30, 6086 is a spore-forming probiotic strain with a published genome sequence. Human RCT evidence includes a trial in school-age children examining immune-related markers during respiratory and gastrointestinal illness, and a separate study examining amino acid absorption from milk protein. In vitro research has examined immune-modulating and anti-inflammatory mechanisms in laboratory settings, and animal studies have examined metabolic markers in rodent models. The spore-forming nature of the strain is associated with heat and processing stability, which has drawn food-industry research interest for use in baked and fermented foods. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 40 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+1 more systems

Symptoms in the research

Share of this strain's 14 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+2 more symptoms

Research

48 papers reference this strain in the probiotic database.

Match confidence
2025 IN_VITRO
Thermal death time kinetics of three Bacillus strain probiotics in peptone media
· SHAREOK (University of Oklahoma; Oklahoma State University; Central Oklahoma University)
2025 ANIMAL
Effects of Bacillus coagulans (GBI-30, 6086) supplementation on apparent total tract nutrient digestibility and the fecal characteristics and metabolites, immunity, and microbiota of healthy adult dogs
· Journal of Animal Science
2025 IN_VITRO
Determining the viability and stability of Bacillus in baked products
· LWT
2025 RCT
Impact of Heyndrickxia (Bacillus) coagulans GBI-30, 6086 (BC30) probiotic on gastrointestinal function in healthy adults: a randomised controlled trial
· Beneficial Microbes
2025 ANIMAL
Effects of Bacillus coagulans (GBI-30, 6086) Supplementation on the Fecal Characteristics and Microbiota of Healthy Adult Dogs Subjected to an Abrupt Diet Change
· Microorganisms
2024 ANIMAL
PSIX-16 Effects of Bacillus coagulans GBI-30, 6086 on nutrient digestibility, fecal characteristics and metabolites, immunity, and microbiota of healthy adult dogs subjected to an abrupt diet change
· Journal of Animal Science
2024 RCT
Oral probiotic administration attenuates postexercise inflammation in horses
· Translational Animal Science
2024 OTHER
Kinetic study of the thermal inactivation of Weizmannia coagulans during food thermal processing
· Heliyon
2024 OTHER
Development and characterization of probiotic pectin candy with jussara and passion fruit
· Ciência e Natura
2023 REVIEW
Overview of Probiotic Strains of Weizmannia coagulans, Previously Known as Bacillus coagulans, as Food Supplements and Their Use in Human Health
· Applied Microbiology
2023 ANIMAL
Alleviative effects of Bacillus coagulans strains on irritable bowel syndrome-unraveling strain specificity through physiological and genomic analysis
· Food Science and Human Wellness
2022 RCT
Probiotic BC30 Improves Amino Acid Absorption from Plant Protein Concentrate in Older Women
· Probiotics and Antimicrobial Proteins
2022 IN_VITRO
Characterization of novel probiotic nanocomposite films based on nano chitosan/ nano cellulose/ gelatin for the preservation of fresh chicken fillets
· LWT
2022 OTHER
Development of intermediate‐moisture apricot with impregnation of Bacillus coagulans GBI‐30 6086 as a functional snack: Quality assessment during storage
· Journal of Food Processing and Preservation
2022 IN_VITRO
Biocontrol of Listeria monocytogenes by Bacillus coagulans GBI-30, 6086 in a synbiotic white brined cheese: An In Vitro model study
· LWT
2022 ANIMAL
Different effects of Bacillus coagulans vegetative cells and spore isolates on constipation-induced gut microbiota dysbiosis in mice
· Food & Function
2021 ANIMAL
Orange Juice and Yogurt Carrying Probiotic Bacillus coagulans GBI-30 6086: Impact of Intake on Wistar Male Rats Health Parameters and Gut Bacterial Diversity
· Frontiers in Microbiology
2021 ANIMAL
PSV-B-18 Characterization of the fecal microbiome of healthy adult beagle dogs supplemented with graded levels of bacillus coagulans GBI-30, 6086
· Journal of Animal Science
2021 OBSERVATIONAL
Probiotic Bacillus coagulans GBI‐30, 6086 Supplementation Improves β‐Hydroxy‐β‐methylbutyrate Bioavailability
· The FASEB Journal
2021 OTHER
Functional Abdominal Pain of Children: Therapy with Bacillus Coagulans GBI-30, 6086 and Insight into Its Probiotic Properties
· Asian Journal of Pediatric Research
Browse all 48 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Impact of Heyndrickxia (Bacillus) coagulans GBI-30, 6086 (BC30) probiotic on gastrointestinal function in healthy adults: a randomised controlled trial
    · Beneficial Microbes · 2025
    PMID 40707016 →
  2. [2]
    Thermal death time kinetics of three Bacillus strain probiotics in peptone media
    · SHAREOK (University of Oklahoma; Oklahoma State University; Central Oklahoma University) · 2025
    Source →
  3. [3]
    Oral probiotic administration attenuates postexercise inflammation in horses
    · Translational Animal Science · 2024
    PMID 39281311 →
  4. [4]
    Alleviative effects of Bacillus coagulans strains on irritable bowel syndrome-unraveling strain specificity through physiological and genomic analysis
    · Food Science and Human Wellness · 2023
    Source →
  5. [5]
    Overview of Probiotic Strains of Weizmannia coagulans, Previously Known as Bacillus coagulans, as Food Supplements and Their Use in Human Health
    · Applied Microbiology · 2023
    Source →
  6. [6]
    Probiotic BC30 Improves Amino Acid Absorption from Plant Protein Concentrate in Older Women
    · Probiotics and Antimicrobial Proteins · 2022
    PMID 36515888 →
  7. [7]
    Bacillus coagulans GBI-30, 6086 improves amino acid absorption from milk protein
    · Nutrition & Metabolism · 2020
    PMID 33110439 →
  8. [8]
    Spores of Bacillus coagulans GBI-30, 6086 show high germination, survival and enzyme activity in a dynamic, computer-controlled in vitro model of the gastrointestinal tract
    · Beneficial Microbes · 2019
    PMID 30694101 →
  9. [9]
    Bacillus coagulans GBI-30, 6068 decreases upper respiratory and gastrointestinal tract symptoms in healthy Mexican scholar-aged children by modulating immune-related proteins
    · Food Research International · 2019
    PMID 31554075 →
  10. [10]
    Immunomodulation of Antiretroviral Drug-Suppressed Chronic HIV-1 Infection in an Oral Probiotic Double-Blind Placebo-Controlled Trial
    · AIDS Research and Human Retroviruses · 2014
    PMID 25127924 →