Strain Profile
· NCBI Species Taxon
1398
NCBI Taxonomy's node for this strain's species, not for the strain itself — NCBI has no strain-level node for it. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
How we classify this →
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Bacillus coagulans
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Environmental
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Bacillus coagulans is a spore-forming bacterium studied as a probiotic candidate, in part because its spores exhibit heat and acid stability, a property studied in relation to survival through food processing and gastric transit. The available strain-specific evidence for this entry is heterogeneous and includes food safety studies, fermentation research, and industrial applications alongside limited probiotic data. A 2020 randomized controlled trial examined a preparation containing B. coagulans alongside another organism (C. butyricum) in the context of Helicobacter pylori eradication, though the multi-organism design limits attribution to this species alone. Genome-based safety assessments exist for certain B. coagulans strains, but efficacy data for this specific unnamed strain are limited. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 748 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 261 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+17 more symptoms
Strains of this species
1 strain of Bacillus coagulans in the index, with 48 linked papers between them.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
1959 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
IN_VITRO
2026
RCT
2026
REVIEW
2026
ANIMAL
2026
ANIMAL
2026
IN_VITRO
2026
ANIMAL
2026
IN_VITRO
2026
OTHER
2026
OTHER
2026
IN_VITRO
2026
ANIMAL
2026
ANIMAL
2026
OTHER
2026
REVIEW
2026
IN_VITRO
2026
REVIEW
2026
IN_VITRO
2026
RCT
2026
IN_VITRO
Browse all 1,959 papers →
Protective effects of Bacillus coagulans and kiwiberry compound on oxidative damage in Caco-2 cells: development of a functional gelatin gummies
· SSRN Electronic Journal
Efficacy and Safety of Bacillus coagulans IDCC 1201 for Sleep Improvement in Adults with Sleep Disturbance: A Randomized, Double-Blind, Placebo-Controlled Polysomnographic Study
· Nutrients
Clinical Evidence for a Bacillus coagulans–Centered Probiotic Composition in Metabolic-Environment Regulation and Weight Management Among Overweight Adults
· Frontiers in Humanities and Social Sciences
Effect of spraying Bacillus coagulans during incubation on hatchability, chick growth, resistance to Mycoplasma synoviae, and cecal microbiota
· Poultry Science
Phycoerythrin nanoemulsion-enriched probiotic sausage: enhancing Bacillus coagulans viability via Aliinostoc sp. 2 exopolysaccharides
· Scientific Reports
Evaluation of antibacterial action of toothpaste containing bacillus coagulans against streptococcus mutans, streptococcus salivarius and its enamel remineralising potential - An in vitro study
· Journal of Contemporary Orthodontics
Bacillus coagulans idrc019 Attenuates Irritable Bowel Syndrome by Revealing Multimodal Protective Mechanisms
· Microorganisms
Combined Effect of Environmental pH and Pulsed Electric Fields on Bacillus Coagulans Vegetative Cells Inactivation
· Processes
Targeting the Microbiota-Gut-Brain Axis: Bacillus coagulans Protects Against Rotenone-Induced Parkinson’s Disease in Rats
· Neurochemical Research
Probiotic potential and characteristics of Bacillus coagulans strain from traditional Indonesian fermented fish products
· Fisheries and aquatic sciences
Effects of Mesoporous Silica Nanoparticles on Seedling Growth of Vigna radiata and Glycolytic Metabolism in Bacillus coagulans
· ACS Agricultural Science & Technology
Genomic analysis, tolerance, and probiotic potential of Bacillus coagulans mr-1B isolated from the hindgut of Macrobrachium rosenbergii against Vibrio parahaemolyticus
· International Microbiology
Effect of Bacillus coagulans DSM 32016 (TechnoSpore®) Supplementation on Growth Performance and Selected Blood Parameters and Serum Urea in Weaning Danube White Pigs
· Life
Multi-omics analysis reveals dietary Bacillus coagulans supplementation improves meat flavor of broiler chickens by modulating gut microbiota and muscle metabolism
· SSRN Electronic Journal
Bacillus coagulans: basic and applied aspects
· Elsevier eBooks
Development and Characterisation of Bacillus coagulans-containing Oral Fast MeltFilm for Oral Health Maintenance
· Current Pharmaceutical Design
What is the effect of Bacillus coagulans supplementation on gut microbiota composition and its potential impact on skin health?
· Zenodo (CERN European Organization for Nuclear Research)
Abstract 2872: E. coli-driven inflammatory and migratory responses in colorectal cancer and modulation by Bacillus coagulans
· Cancer Research
Therapeutic Potential of Bacillus Coagulans Unique IS2 Probiotic Supplementation on Early Periodontitis Patients: A Randomized Controlled Trial
· International Arab Journal of Dentistry
Screening of a 4-Ethylguaiacol-Producing Bacillus coagulans JN11 and Characterization of Its Phenolic Acid Decarboxylase BcPAD
· Preprints.org
Discussion
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Citations
Selected papers that name this strain.
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[1]
Source →Therapeutic Potential of Bacillus Coagulans Unique IS2 Probiotic Supplementation on Early Periodontitis Patients: A Randomized Controlled Trial· International Arab Journal of Dentistry · 2026
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[2]
PMID 42196985 →Efficacy and Safety of Bacillus coagulans IDCC 1201 for Sleep Improvement in Adults with Sleep Disturbance: A Randomized, Double-Blind, Placebo-Controlled Polysomnographic Study· Nutrients · 2026
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[3]
Source →Heyndrickxia coagulans as a Next-Generation ProbioticHeyndrickxia Coagulans как пробиотик нового поколения· Ernst Journal of Animal Science · 2026
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[4]
PMID 41641154 →Oral health benefits of Heyndrickxia coagulans: a systematic review and meta-analysis of current evidence· Frontiers in Oral Health · 2026
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[5]
PMID 41915321 →Genomic analysis, tolerance, and probiotic potential of Bacillus coagulans mr-1B isolated from the hindgut of Macrobrachium rosenbergii against Vibrio parahaemolyticus· International Microbiology · 2026
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[6]
Source →Supplementation of horses with B. coagulans GBI-30,6086 protects against gastrointestinal inflammation· Journal of Equine Veterinary Science · 2025
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[7]
PMID 40416368 →Effect of Bacillus coagulans BC99 supplementation on body weight and gut microbiota in overweight and obese individual: a randomized, double-blind, placebo-controlled study· Frontiers in Nutrition · 2025
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[8]
PMID 41262831 →Testing the Immunomodulatory Effects of Probiotic Bacillus coagulans SNZ 1969® in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial· Cureus · 2025
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[9]
PMID 40456531 →Bacillus coagulans Unique IS2 improves stool characteristics in healthy adults with infrequent bowel movements: a randomized, double-blind, placebo-controlled trial· Beneficial Microbes · 2025
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[10]
Source →A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety of Heat-Inactivated Heyndrickxia Coagulans Mtcc 5856 (Immunospore®) in Healthy Human Participants· SSRN Electronic Journal · 2025