Strain Profile
· NCBI Species Taxon
1398
NCBI Taxonomy's node for this strain's species, not for the strain itself — NCBI has no strain-level node for it. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
How we classify this →
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Bacillus coagulans
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Environmental
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Bacillus coagulans is a spore-forming bacterium studied as a probiotic candidate, in part because its spores exhibit heat and acid stability, a property studied in relation to survival through food processing and gastric transit. The available strain-specific evidence for this entry is heterogeneous and includes food safety studies, fermentation research, and industrial applications alongside limited probiotic data. A 2020 randomized controlled trial examined a preparation containing B. coagulans alongside another organism (C. butyricum) in the context of Helicobacter pylori eradication, though the multi-organism design limits attribution to this species alone. Genome-based safety assessments exist for certain B. coagulans strains, but efficacy data for this specific unnamed strain are limited. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 748 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 261 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+17 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
1959 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
OTHER
2026
IN_VITRO
2026
IN_VITRO
2026
IN_VITRO
2026
IN_VITRO
2026
REVIEW
2026
ANIMAL
2026
IN_VITRO
2026
IN_VITRO
2026
IN_VITRO
2026
META_ANALYSIS
2026
REVIEW
2026
IN_VITRO
2026
ANIMAL
2026
ANIMAL
2026
ANIMAL
2026
ANIMAL
2026
REVIEW
2026
RCT
2026
IN_VITRO
Browse all 1,959 papers →
Heyndrickxia coagulans JF1 with potent ethanol-degrading capacity: In vitro screening and functional characterization
· Food Bioscience
Abstract 2872: E. coli-driven inflammatory and migratory responses in colorectal cancer and modulation by Bacillus coagulans
· Cancer Research
Effect of Coating and Impregnation on the Quality and Probiotic Viability of Freeze-Dried Apple Snacks
· Asian Journal of Dairy and Food Research
Investigation of the Carbon Catabolite Repression Mechanism in L-Lactic Acid Fermentation from Mixed Sugars by Bacillus coagulans DSM 2314
· Microorganisms
Development and Characterisation of Bacillus coagulans-containing Oral Fast MeltFilm for Oral Health Maintenance
· Current Pharmaceutical Design
What is the effect of Bacillus coagulans supplementation on gut microbiota composition and its potential impact on skin health?
· Zenodo (CERN European Organization for Nuclear Research)
Food-Form Delivery of Spore-Forming Probiotics as an Alternative to Gavage in Animal Models
· Utah State Research and Scholarship (Utah State University)
Efficient L-lactic acid production from corncob by deep eutectic solvent pretreatment with reduced washing demand
· Industrial Crops and Products
Comparative Stability of Heyndrickxia coagulans Spores in Oat and Rice-Bean Matrices: Impact of Processing, Storage, and Simulated Digestion
· Processes
Optimization of Process Conditions for Production of Succinic Acid and Lactic Acids from Cake Waste Using Response Surface Methodology
· Journal of Agricultural Engineering (India)
Oral health benefits of Heyndrickxia coagulans: a systematic review and meta-analysis of current evidence
· Frontiers in Oral Health
Bacillus coagulans: basic and applied aspects
· Elsevier eBooks
Formulation and Evaluation of Oral Drop for the Treatment of Gastrointestinal Disorder in Infants
· International Journal of Drug Delivery Technology
Bacillus coagulans idrc019 Attenuates Irritable Bowel Syndrome by Revealing Multimodal Protective Mechanisms
· Microorganisms
EEG and Metabolite Profiling in Mouse Model
· Zenodo (CERN European Organization for Nuclear Research)
Microbial sleep modulation reshapes metabolic networks and cortical dynamics distinct from pharmacological intervention
· Zenodo (CERN European Organization for Nuclear Research)
Dietary supplementation of lactic acid bacteria probiotics enhances growth and feed efficiency in Penaeus monodon
· IOP Conference Series Earth and Environmental Science
Heyndrickxia coagulans as a Next-Generation Probiotic
Heyndrickxia Coagulans как пробиотик нового поколения
· Ernst Journal of Animal Science
Effects of Weizmannia faecalis DSM 32016 and Bacillus licheniformis DSM 33806–Based Probiotics on Performance, Carcass Traits, and Intestinal Health of Broilers
· Animals
Combined Effect of Environmental pH and Pulsed Electric Fields on Bacillus Coagulans Vegetative Cells Inactivation
· Processes
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 42196985 →Efficacy and Safety of Bacillus coagulans IDCC 1201 for Sleep Improvement in Adults with Sleep Disturbance: A Randomized, Double-Blind, Placebo-Controlled Polysomnographic Study· Nutrients · 2026
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[2]
Source →Heyndrickxia coagulans as a Next-Generation ProbioticHeyndrickxia Coagulans как пробиотик нового поколения· Ernst Journal of Animal Science · 2026
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[3]
PMID 41915321 →Genomic analysis, tolerance, and probiotic potential of Bacillus coagulans mr-1B isolated from the hindgut of Macrobrachium rosenbergii against Vibrio parahaemolyticus· International Microbiology · 2026
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[4]
PMID 41641154 →Oral health benefits of Heyndrickxia coagulans: a systematic review and meta-analysis of current evidence· Frontiers in Oral Health · 2026
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[5]
Source →Therapeutic Potential of Bacillus Coagulans Unique IS2 Probiotic Supplementation on Early Periodontitis Patients: A Randomized Controlled Trial· International Arab Journal of Dentistry · 2026
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[6]
Source →Supplementation of horses with B. coagulans GBI-30,6086 protects against gastrointestinal inflammation· Journal of Equine Veterinary Science · 2025
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[7]
PMID 41262831 →Testing the Immunomodulatory Effects of Probiotic Bacillus coagulans SNZ 1969® in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial· Cureus · 2025
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[8]
PMID 40456531 →Bacillus coagulans Unique IS2 improves stool characteristics in healthy adults with infrequent bowel movements: a randomized, double-blind, placebo-controlled trial· Beneficial Microbes · 2025
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[9]
Source →A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety of Heat-Inactivated Heyndrickxia Coagulans Mtcc 5856 (Immunospore®) in Healthy Human Participants· SSRN Electronic Journal · 2025
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[10]
PMID 40416368 →Effect of Bacillus coagulans BC99 supplementation on body weight and gut microbiota in overweight and obese individual: a randomized, double-blind, placebo-controlled study· Frontiers in Nutrition · 2025