Cutibacterium acnes

Wogonin Ameliorates the Oxidative Stress, Apoptosis, and Extracellular Matrix Degradation of Nucleus Pulposus Cells Mediated by Cutibacterium acnes via the MAPK Signaling Pathway: An In Vivo and In Vitro Study

AKNE PATOGENEZIDA TERI MIKROBIOMASINING ROLI

Intervertebral disc puncture predisposes the disc to Cutibacterium acnes infection via hematogenous and contiguous routes: a rat model study

The Effect of Microneedling Mesotherapy, Chemical Exfoliation and Combination Therapy on Selected Skin Parameters and Cutibacterium acnes Colonization in Women With Oily Skin

Preliminary characterization of the skin microbiota in basal cell carcinoma: An exploratory pilot study in Korean patients

Cutibacterium acnes (C. acnes) is a common skin commensal associated with acne pathogenesis. Here, we investigated the capacity of acne-associated (CA) and healthy skin-associated (CH) C. acnes strains to induce extracellular trap (ET) formation in human neutrophils (NETs) and Th17 cells (TETs) and performed proteomic analyses to define their molecular signatures. NETs displayed a conserved protein profile regardless of the C. acnes strain, whereas TETs exhibited strain-specific proteomic profiles. CA-induced TETs were enriched in inflammatory and extracellular matrix remodeling proteins, while CH-induced TETs showed upregulation of nuclear, mitochondrial, and antimicrobial proteins, including granulysin, granzyme B, and cathepsin C. These findings underscore strain- and cell type-specific regulation of ET formation and suggest that CH-induced TETs may contribute to skin immune homeostasis, whereas CA-induced TETs may promote inflammatory and tissue remodeling responses in acne. Our study reveals a potential mechanism by which skin microbiota differentially modulates Th17 effector programs, ultimately influencing downstream immune activity and skin health.

Cutibacterium acnes and Acne Vulgaris: A Narrative Review of Epidemiology, Pathogenesis, Diagnosis, Management, and Future Perspectives

Pseudolysogeny-mediated evolutionary trade-offs favor phage therapy by limiting antibiotic resistance and virulence in Cutibacterium acnes

Unraveling the Enigmatic Behavior of Cutibacterium acnes: Exploring Clinical Correlations and Behaviors of Clinical Strains in Prosthetic Joint Infections

Microbiome-Derived Indole-3-Lactic Acid Attenuates Cutibacterium Acnes-Induced Inflammation via the Aryl Hydrocarbon Receptor Pathway

Antibacterial and antibiofilm effects of Rosa damascena extracts on clinical isolates of Cutibacterium acnes

Scalp Microbiome Alterations in Androgenetic Alopecia: Patterns and Emerging Mechanistic Insights

Endogenous Hypersensitivity Infection: A Unifying Framework for Cutibacterium acnes-Associated Sarcoidosis

Acne Infection (Acne Vulgaris) and the Relationship between Cutibacterium Acnes Colonization and Severity

Antimicrobial photodynamic therapy using sodium iron chlorophyllin against drug-resistant Cutibacterium acnes from patients with acne vulgaris

Pulmonary Abscess Caused by Cutibacterium acnes in an Immunocompetent Patient: A Case Report and Review of the Literature

Cutibacterium acnes inhibits Staphylococcus lugdunensis biofilm formation through inhibition of autolysis and purine biosynthesis

UMI-guided single locus sequence typing method for phylotyping Cutibacterium acnes from skin samples

Enhancing Antibacterial Activity of Medinilla speciosa Blume Fruits Against Cutibacterium acnes Through Phytosome Delivery: An In Vivo Study

Pathophysiology of Acne Vulgaris: An Integrative Narrative Review