Strain Profile
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Lactobacillus paracasei F19
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus paracasei F19 is a probiotic strain that has been studied in human feeding studies spanning multiple cohorts. A randomized controlled trial investigated its role in the context of gastrointestinal side effects associated with proton pump inhibitor use, and early-life intervention studies have examined tolerability in infants and children. Most mechanistic research is in vitro, exploring growth in the presence of prebiotics and behavior under food-processing conditions such as microwave drying and incorporation into fermented foods. Evidence for specific health benefits remains preliminary and mostly preclinical or exploratory. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 25 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+2 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 13 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+4 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
39 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2026
IN_VITRO
2026
ANIMAL
2026
ANIMAL
2025
ANIMAL
2024
ANIMAL
2022
IN_VITRO
2022
IN_VITRO
2022
OBSERVATIONAL
2021
ANIMAL
2019
IN_VITRO
2018
IN_VITRO
2017
ANIMAL
2017
IN_VITRO
2017
IN_VITRO
2015
RCT
2014
RCT
2014
IN_VITRO
2013
RCT
2013
IN_VITRO
2013
IN_VITRO
Browse all 39 papers →
Flavorful Microbial Fermentation: Metabolic, Flavoromic, and Sensory Analysis Insights Into Probiotic‐Enhanced Catharina Sour Beer With Lacticaseibacillus paracasei F19
· International Journal of Microbiology
Pharmacological modulation of the gut microbiota and epithelial barrier: new therapeutic perspectives in obesity
· IRIS Research product catalog (Sapienza University of Rome)
Engineered PEA-producing Lactobacillus paracasei F19 prevents colitis-associated colorectal cancer in mice by modulating inflammatory–angiogenic signaling and beneficially reshapes gut microbiota composition
· Biomedicine & Pharmacotherapy
Oleoylethanolamide-producing Lactobacillus paracasei F19 improves metabolic and behavioral disorders by restoring intestinal permeability and microbiota-gut-brain axis in high-fat diet-induced obese male mice
· Brain Behavior and Immunity
Intranasal delivery of PEA-producing Lactobacillus paracasei F19 alleviates SARS-CoV-2 spike protein-induced lung injury in mice
· Translational Medicine Communications
Sour beer formulation added with bagasse and fruit juice: probiotic potential and sensory evaluation
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Formulação de cerveja Sour com bagaço e suco de fruta: potencial probiótico e avaliação sensorial
· Digital Library of Theses and Dissertations (Universidade de São Paulo)
Metabolic Phenotype and Microbiome of Infants Fed Formula Containing Lactobacillus paracasei Strain F-19
· Frontiers in Pediatrics
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice
· International Journal of Molecular Sciences
Influence of hot and cold break tomato powders on survival of probiotic L. paracasei subsp. paracasei F19, texture profile and antioxidative activity in set-type yoghurts
· LWT
Structural basis of the impact of microwave drying on survival and shelf life of Lactobacillus paracasei
· LWT
Supplementation with Lactobacillus paracasei or Pediococcus pentosaceus does not prevent diarrhoea in neonatal pigs infected with Escherichia coli F18
· British Journal Of Nutrition
Boosting the growth of the probiotic strain Lactobacillus paracasei ssp. paracasei F19
· Archives of Microbiology
Temperature-controlled microwave-vacuum drying of lactic acid bacteria: Impact of drying conditions on process and product characteristics
· Journal of Food Engineering
Lactobacillus paracasei F19 versus placebo for the prevention of proton pump inhibitor-induced bowel symptoms: A randomized clinical trial
· Digestive and Liver Disease
Abstract
· Dental Update
OC.08.4 ENTEROGLIAL CELLS–BACTERIA INTERACTION MODULATES INTESTINAL EPITHELIAL CELLS DIFFERENTIATION
· Digestive and Liver Disease
Early Intervention with Probiotic Lactobacillus paracasei F19 Has No Long-Term Effect on Caries Experience
· Caries Research
Enteroglial-derived S100B protein integrates bacteria-induced Toll-like receptor signalling in human enteric glial cells
· Gut
Drying Kinetics and Survival of Bacteria Suspensions of L. paracasei F19 in Low-Temperature Vacuum Drying
· Drying Technology
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 42574976 →Engineered PEA-producing Lactobacillus paracasei F19 prevents colitis-associated colorectal cancer in mice by modulating inflammatory–angiogenic signaling and beneficially reshapes gut microbiota composition· Biomedicine & Pharmacotherapy · 2026
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[2]
PMID 35558362 →Metabolic Phenotype and Microbiome of Infants Fed Formula Containing Lactobacillus paracasei Strain F-19· Frontiers in Pediatrics · 2022
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[3]
PMID 25660822 →Lactobacillus paracasei F19 versus placebo for the prevention of proton pump inhibitor-induced bowel symptoms: A randomized clinical trial· Digestive and Liver Disease · 2015
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[4]
PMID 21372765 →Efficacy of Lactobacillus paracasei sub. paracasei F19 on abdominal symptoms in patients with symptomatic uncomplicated diverticular disease: a pilot study.· Computer Und Recht: Forum für die Praxis des Rechts der Datenverargeitung, Information und Automation · 2011
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[5]
Source →Lactobacillus paracasei subsp. paracasei F19: Survival, Ecology and Safety in the Human Intestinal Tract - A Survey of Feeding Studies within the PROBDEMO Project· Microbial Ecology in Health and Disease · 2002
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[6]
Source →Isolation, Selection and Characteristics of Lactobacillus paracasei subsp. paracasei F19· Microbial Ecology in Health and Disease · 2002