Strain Profile
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Lactobacillus plantarum HEAL9
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus plantarum HEAL9 is a well-characterized lactic acid bacterium studied for its immunomodulatory properties. Research in both human and animal models has examined inflammatory markers, with randomized controlled trials exploring stress resilience, mood, and immune function. In vitro and animal studies have examined possible mechanisms related to gut-brain interactions, and human clinical efficacy for specific health outcomes remains an active area of investigation. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 9 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+1 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 3 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
22 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2025
ANIMAL
2024
RCT
2023
RCT
2023
ANIMAL
2020
RCT
2020
RCT
2019
RCT
2013
RCT
2025
REVIEW
2022
ANIMAL
2026
REVIEW
2026
ANIMAL
2024
ANIMAL
2024
OTHER
2024
RCT
2023
REVIEW
2023
RCT
2023
RCT
2021
RCT
2020
RCT
Browse all 22 papers →
Toxic effects of lead, cadmium, mercury and arsenic mixture in a subacute exposure model for rats: protective effect of probiotics
· National Repository of Dissertations in Serbia
Probiotic-Reduced Inflammaging in Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial
· Probiotics and Antimicrobial Proteins
Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study
· Nutrients
26 LACTIPLANTIBACILLUS PLANTARUM HEAL9 AS A SUITABLE APPROACH TARGETING MICROBIOTA GUT-BRAIN AXIS FOR THE ALLEVIATION OF ALZHEIMER'S DISEASE AND RELATED BOWEL SYMPTOMS
· Gastroenterology
Intake of Lactiplantibacillus plantarum HEAL9 reduces the inflammatory markers soluble fractalkine and CD163 during acute stress: A randomized, double blind, placebo-controlled study
· Physiology & Behavior
Oral Administration of S-Adenosylmethionine (SAMe) and Lactobacillus Plantarum HEAL9 Improves the Mild-To-Moderate Symptoms of Depression
· The Primary Care Companion For CNS Disorders
Effects of Lactobacillus plantarum and Lactobacillus paracasei on the Peripheral Immune Response in Children with Celiac Disease Autoimmunity: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
· Nutrients
Randomized, Double Blind and Placebo Controlled Study Using a Combination of Two Probiotic Lactobacilli to Alleviate Symptoms and Frequency of Common Cold
· Food and Nutrition Sciences
Is There a Future Without Gluten Restrictions for Celiac Patients? Update on Current Treatments
· Nutrients
Probiotics Inhibit Cartilage Damage and Progression of Osteoarthritis in Mice
· Calcified Tissue International
Clinical and Translational Evidence for BALIMONT, a Lactobacillus acidophilus-Centered Biotic Composition, in Modulating Immune-Inflammatory Responses
· Scientific Journal of Technology
Fermo-Food for Diarrheic or Constipated Cats: Fermented Turmeric (Curcuma longa L.) Alleviated Fecal ConsistencyFermo-Food for Diarrheic or Constipated Cats: Fermented Turmeric (Curcuma longa L.) Alleviated Fecal Consistency
· Acta fytotechnica et zootechnica/Acta fytotechnica et zootechnica
Lactiplantibacillus plantarum HEAL9 attenuates cognitive impairment and progression of Alzheimer's disease and related bowel symptoms in SAMP8 mice by modulating microbiota-gut-inflammasome-brain axis
· Food & Function
Correction: Lactiplantibacillus plantarum HEAL9 attenuates cognitive impairment and progression of Alzheimer's disease and related bowel symptoms in SAMP8 mice by modulating microbiota-gut-inflammasome-brain axis
· Food & Function
730 LACTIPLANTIBACILLUS PLANTARUM HEAL9 REDUCES FECAL CALPROTECTIN LEVELS IN ELDERLY INDIVIDUALS WITH LOW-GRADE INFLAMMATION
· Gastroenterology
Efficacy of probiotics supplementation in amelioration of celiac disease symptoms and enhancement of immune system
· World Journal of Clinical Cases
Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the faecal metabolome in children with coeliac disease autoimmunity: a randomised, double-blinded placebo-controlled clinical trial
· Frontiers in Nutrition
Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the single-cell fecal parasitome in children with celiac disease autoimmunity: a randomized, double-blind placebo-controlled clinical trial
· Parasites & Vectors
Effects of Probiotic Bacteria Lactobacillaceae on the Gut Microbiota in Children With Celiac Disease Autoimmunity: A Placebo-Controlled and Randomized Clinical Trial
· Frontiers in Nutrition
Fewer Community-Acquired Colds with Daily Consumption of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2. A Randomized, Placebo-Controlled Clinical Trial
· Journal of Nutrition
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Citations
Selected papers that name this strain.
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[1]
Source →Clinical and Translational Evidence for BALIMONT, a Lactobacillus acidophilus-Centered Biotic Composition, in Modulating Immune-Inflammatory Responses· Scientific Journal of Technology · 2026
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[2]
Source →Toxic effects of lead, cadmium, mercury and arsenic mixture in a subacute exposure model for rats: protective effect of probiotics· National Repository of Dissertations in Serbia · 2025
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[3]
PMID 38073702 →Efficacy of probiotics supplementation in amelioration of celiac disease symptoms and enhancement of immune system· World Journal of Clinical Cases · 2023
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[4]
PMID 37485388 →Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the faecal metabolome in children with coeliac disease autoimmunity: a randomised, double-blinded placebo-controlled clinical trial· Frontiers in Nutrition · 2023
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[5]
PMID 32687924 →Intake of Lactiplantibacillus plantarum HEAL9 reduces the inflammatory markers soluble fractalkine and CD163 during acute stress: A randomized, double blind, placebo-controlled study· Physiology & Behavior · 2020
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[6]
Source →Randomized, Double Blind and Placebo Controlled Study Using a Combination of Two Probiotic Lactobacilli to Alleviate Symptoms and Frequency of Common Cold· Food and Nutrition Sciences · 2013