Strain Profile
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Bifidobacterium animalis
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Bifidobacterium animalis (undesignated strain) is a species-level entry; most clinical evidence in the literature is concentrated in named subspecies strains such as B. animalis subsp. lactis BB-12 and BL04. RCT evidence for those named strains has examined gut microbiota composition, constipation, immune response in the context of influenza vaccination, and oral health, but attributing these study topics to an undesignated B. animalis entry is not scientifically appropriate. Probiotic research in Bifidobacterium is highly strain-specific, and a strain designation is needed to characterize evidence meaningfully. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 98 body-system-tagged papers that concern each system. Research coverage, not measured effect.
+4 more systems
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 47 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
157 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2024
RCT
2022
ANIMAL
2022
ANIMAL
2022
REVIEW
2022
ANIMAL
2021
OTHER
2021
ANIMAL
2021
RCT
2021
IN_VITRO
2021
ANIMAL
2021
REVIEW
2021
ANIMAL
2020
RCT
2020
ANIMAL
2020
ANIMAL
2020
REVIEW
2020
ANIMAL
2020
ANIMAL
2020
RCT
2020
ANIMAL
Browse all 157 papers →
Efficacy of Bifidobacterium animalis subsp. lactis BL-99 in the treatment of functional dyspepsia: a randomized placebo-controlled clinical trial
· Nature Communications
Anti-inflammatory effect of Bifidobacterium animalis subsp. lactis A6 on DSS-induced colitis in mice
· Journal of Applied Microbiology
Bifidobacterium animalis Promotes the Growth of Weaning Piglets by Improving Intestinal Development, Enhancing Antioxidant Capacity, and Modulating Gut Microbiota
· Applied and Environmental Microbiology
Use of the Probiotic Bifidobacterium animalis subsp. lactis HN019 in Oral Diseases
· International Journal of Molecular Sciences
Effect of Bifidobacterium animalis subsp. lactis SF on enhancing the tumor suppression of irinotecan by regulating the intestinal flora
· Pharmacological Research
Microencapsulation of Lactobacillus acidophilus LA‐5 and Bifidobacterium animalis BB‐12 in pectin and sodium alginate: A comparative study on viability, stability, and structure
· Food Science & Nutrition
Lipoteichoic acid from Bifidobacterium animalis subsp. lactis BPL1: a novel postbiotic that reduces fat deposition via IGF‐1 pathway
· Microbial Biotechnology
Bifidobacterium animalis subsp. lactis BB-12 Protects against Antibiotic-Induced Functional and Compositional Changes in Human Fecal Microbiome
· Nutrients
Microencapsulation and invitro characterization of Bifidobacterium animalis for improved survival
· Journal of Food Measurement & Characterization
Alleviation Effects of Bifidobacterium animalis subsp. lactis XLTG11 on Dextran Sulfate Sodium-Induced Colitis in Mice
· Microorganisms
Bifidobacterium animalis subsp. lactis HN019 Effects on Gut Health: A Review
· Frontiers in Nutrition
Bifidobacterium animalis subsp. lactis lkm512 Attenuates Obesity‐Associated Inflammation and Insulin Resistance Through the Modification of Gut Microbiota in High‐Fat Diet‐Induced Obese Mice
· Molecular Nutrition & Food Research
Bifidobacterium animalis subsp lactis HN019 presents antimicrobial potential against periodontopathogens and modulates the immunological response of oral mucosa in periodontitis patients
· PLoS ONE
Bifidobacterium animalis subsp. lactis GCL2505 modulates host energy metabolism via the short-chain fatty acid receptor GPR43
· Scientific Reports
Bifidobacterium animalis: the missing link for the cancer-preventive effect of Gynostemma pentaphyllum
· Gut Microbes
Bifidobacterium animalis subsp. lactis 420 for Metabolic Health: Review of the Research
· Nutrients
Bifidobacterium animalis subsp. lactis A6 Alleviates Obesity Associated with Promoting Mitochondrial Biogenesis and Function of Adipose Tissue in Mice
· Molecules
Influenza infection elicits an expansion of gut population of endogenous Bifidobacterium animalis which protects mice against infection
· Genome biology
PHAGE-2 Study: Supplemental Bacteriophages Extend Bifidobacterium animalis subsp. lactis BL04 Benefits on Gut Health and Microbiota in Healthy Adults
· Nutrients
Bifidobacterium animalis ssp. Lactis 420 Mitigates Autoimmune Hepatitis Through Regulating Intestinal Barrier and Liver Immune Cells
· Frontiers in Immunology
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Citations
Selected papers that name this strain.
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[1]
PMID 38172093 →Efficacy of Bifidobacterium animalis subsp. lactis BL-99 in the treatment of functional dyspepsia: a randomized placebo-controlled clinical trial· Nature Communications · 2024
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[2]
PMID 34970580 →Bifidobacterium animalis subsp. lactis HN019 Effects on Gut Health: A Review· Frontiers in Nutrition · 2021
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[3]
PMID 34444974 →Bifidobacterium animalis subsp. lactis BB-12 Protects against Antibiotic-Induced Functional and Compositional Changes in Human Fecal Microbiome· Nutrients · 2021
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[4]
PMID 33308038 →Effect of Bifidobacterium animalis subsp. lactis MN-Gup on constipation and the composition of gut microbiota· Beneficial Microbes · 2020
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[5]
PMID 32824480 →PHAGE-2 Study: Supplemental Bacteriophages Extend Bifidobacterium animalis subsp. lactis BL04 Benefits on Gut Health and Microbiota in Healthy Adults· Nutrients · 2020
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[6]
PMID 33066107 →Effects of Bifidobacterium animalis Subsp. lactis (BPL1) Supplementation in Children and Adolescents with Prader–Willi Syndrome: A Randomized Crossover Trial· Nutrients · 2020
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[7]
PMID 32218248 →Bifidobacterium animalis subsp. lactis 420 for Metabolic Health: Review of the Research· Nutrients · 2020
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[8]
PMID 32960889 →Bifidobacterium animalis subsp lactis HN019 presents antimicrobial potential against periodontopathogens and modulates the immunological response of oral mucosa in periodontitis patients· PLoS ONE · 2020
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[9]
PMID 31797399 →The therapeutic efficacy of Bifidobacterium animalis subsp. lactis BB‐12® in infant colic: A randomised, double blind, placebo‐controlled trial· Alimentary Pharmacology & Therapeutics · 2019
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[10]
PMID 30262813 →Effects of daily consumption of the probiotic Bifidobacterium animalis subsp. lactis CECT 8145 on anthropometric adiposity biomarkers in abdominally obese subjects: a randomized controlled trial· International Journal of Obesity · 2018