Strain Profile
· NCBI Species Taxon
239935
NCBI Taxonomy's node for this strain's species, not for the strain itself — NCBI has no strain-level node for it. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
How we classify this →
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Akkermansia muciniphila
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Human-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Akkermansia muciniphila is a gut bacterium that naturally inhabits the mucus layer lining the intestine and has attracted substantial scientific interest as a potential next-generation probiotic. Observational studies in humans have examined its abundance in the gut microbiome, and animal research has examined markers of metabolic health, intestinal barrier function (the gut's physical defense layer), and immune responses relevant to inflammation and cancer immunotherapy. A pasteurized (heat-treated) form has been studied in mouse models in the context of gut barrier function. Most evidence is preclinical; human intervention trials are early-stage, and no health claims can yet be made based on the current state of research. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 2,772 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 1,132 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+15 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
3291 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
ANIMAL
2026
REVIEW
2026
IN_VITRO
2026
OBSERVATIONAL
2026
OTHER
2026
ANIMAL
2026
ANIMAL
2026
REVIEW
2026
ANIMAL
2026
IN_VITRO
2026
ANIMAL
2026
REVIEW
2026
REVIEW
2026
OBSERVATIONAL
2026
OTHER
2026
ANIMAL
2026
REVIEW
2026
WGS
2026
ANIMAL
2026
IN_VITRO
Browse all 3,291 papers →
The protective effect of Bifidobacterium bifidum G9-1 against mucus degradation by Akkermansia muciniphila following small intestine injury caused by a proton pump inhibitor and aspirin
· Institutional Repositories DataBase (IRDB)
Akkermansia muciniphila in cardiovascular diseases: opportunities and challenges
· Frontiers in Microbiology
Mucin-derived sugars act as metabolic brakes controlling growth initiation in Akkermansia muciniphila
· Gut Microbes
Akkermansia muciniphila enhances washed microbiota transplantation in the treatment of epilepsy
· Chinese Medical Journal
Crystal structure of the thioredoxin domain of Amuc_2173 from Akkermansia muciniphila
· Worldwide Protein Data Bank
Solubilized lignin promotes the growth of Akkermansia muciniphila and improves insulin sensitivity
· Biochemical and Biophysical Research Communications
An Intravesical Akkermansia muciniphila ‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer
· Advanced Science
Decoding Akkermansia muciniphila Effector Biology: From Microbial Molecules to Host Outcomes
· MicrobiologyOpen
Akkermansia muciniphila supplementation alters inflammatory profiles across diverse models of colitis
· Scientific Reports
Unique adaptations in sulfatases underpin colonic mucin degradation by Akkermansia muciniphila
· Nature Microbiology
A phase-variable capsule facilitates Akkermansia muciniphila colonization of the intestinal mucus layer
· mBio
Akkermansia muciniphila : a member of the gut microbiota that modulates intestinal stem cell function
· Physiological Genomics
Pasteurised Akkermansia muciniphila in obesity and metabolic syndrome: mechanisms of action and clinical potential
· Rational Pharmacotherapy in Cardiology
IDDF2026-ABS-0422 Akkermansia muciniphila enhances washed microbiota transplantation in the treatment of epilepsy
· Clinical Gastroenterology
Antigenic mimicry by Akkermansia muciniphila drives IgA nephropathy
· Research Square
Enrichment of Akkermansia muciniphila by red ginseng promotes GDF15 secretion and suppresses obesity in mice
· Phytomedicine
Akkermansia muciniphila : où en est la preuve clinique en 2026 ? (méta-synthèse)
· Zenodo (CERN European Organization for Nuclear Research)
Genome and antiSMASH biosynthetic gene cluster prediction data for Akkermansia muciniphila ATCC BAA-835
· Zenodo (CERN European Organization for Nuclear Research)
Akkermansia muciniphila prevents cadmium-induced cognitive impairment through gut microbiome–mediated mechanisms
· bioRxiv (Cold Spring Harbor Laboratory)
Mechanism of Akkermansia muciniphila in Ameliorating Intestinal Barrier Damage
· DOAJ (DOAJ: Directory of Open Access Journals)
Discussion
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Citations
Selected papers that name this strain.
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[1]
Source →Akkermansia muciniphila Alleviates Circadian Rhythm Disruption-Induced Intestinal Barrier Injury via Activation of the KEAP1-NRF2 Pathway· Research Square · 2026
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[2]
PMID 42625391 →Effects of GLP ‐1 agonists on the gut microbiota in type 2 diabetes mellitus: a systematic review· FEBS Journal · 2026
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[3]
Source →The Gut Microbiome as a Metabolic Signalling Organ in Obesity: From Energy Harvest to Immune Regulation· Preprints.org · 2026
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[4]
Source →The gut microbiome–tumor microenvironment axis in immunotherapy response: Mechanistic insights and clinical implications· International Journal of Molecular and Immuno Oncology · 2026
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[5]
PMID 42493609 →Gut Microbiome in Depression with and without REM Sleep Behavior Disorder· Molecular Psychiatry · 2026
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[6]
PMID 42353998 →Gut Microbiome Responses to Nutritional and Lifestyle Interventions in Pediatric Obesity: A Systematic Review Toward Precision Nutrition· Children · 2026
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[7]
Source →Akkermansia muciniphila remains a beneficial symbiont with therapeutic promise: navigating context-dependent functions of next-generation probiotics· Food, Nutrition and Health. · 2026
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[8]
PMID 41646967 →Collecting the evidence: mechanistic insights into Akkermansia muciniphila’s impact on aging and systemic inflammation· Frontiers in Immunology · 2026
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[9]
Source →Akkermansia and Bacteroides Abundance, Significance, and Therapeutic Potential in Obesity and Associated Metabolic Dysfunction by Systematic Review of Clinical and Sequencing Data· Zenodo (CERN European Organization for Nuclear Research) · 2026
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[10]
PMID 42060851 →Microbe on the move: Akkermansia in infectious diseases and emerging roles in gynecological health· Journal of Bacteriology · 2026