Strain Profile · NCBI Strain Taxon 568703
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Lacticaseibacillus rhamnosus GG

◐ Food-origin
Sequenced
Public genome assembly available

Lacticaseibacillus rhamnosus GG (LGG) is one of the most extensively studied probiotic strains globally, though the papers linked to this strain entry focus primarily on encapsulation technology and formulation stability rather than clinical efficacy — examining how LGG survives in foods like apple juice, yogurt, and chocolate. In vitro studies have examined LGG's interactions with the gut microbiome during antibiotic exposure and activity against certain pathogenic bacteria. The broader LGG literature, not captured in this strain's linked papers, includes numerous human clinical trials across digestive and immune outcomes; strain-specific summaries here are grounded only in the indexed evidence, which is largely formulation-focused. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 2,224 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+6 more systems

Symptoms in the research

Share of this strain's 888 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+17 more symptoms

Research

3593 papers reference this strain in the probiotic database.

Match confidence
OTHER
Development of a Frozen Meat Semi-Finished Product with the Probiotic Culture Lacticaseibacillus rhamnosus GG
Разработка замороженного мясного полуфабриката с пробиотической культурой Lacticaseibacillus rhamnosus GG
· CyberLeninK (CyberLeninka)
IN_VITRO
Should the drug resistance of probiotic strains be extrapolated and should it be based on species or the given strain with regards to 5th generation cephalosporins?
· Jagiellonian University Repository (Jagiellonian University)
OTHER
Integrazione di approcci omici per la caratterizzazione di batteri intestinali chiave: dalla modulazione della comunita microbica all’analisi funzionale del singolo ceppo
· IRIS UNIMORE (University of Modena and Reggio Emilia)
2026 REVIEW
Probiotici u pedijatrijskoj gastroenterologiji
· Paediatria Croatica
2026 IN_VITRO
Fabrication and characterization of a novel Lacticaseibacillus rhamnosus-loaded sulfhydryl-modified pectin/chitosan oligosaccharide composite hydrogel: a dual strategy for enhanced viability and mucoadhesion
· Food Hydrocolloids
2026 IN_VITRO
From Shelf to Self: Assessing the Journey of Lactobacillus rhamnosus GG Survival in Various Beverages
· Zenodo (CERN European Organization for Nuclear Research)
2026 OTHER
Enumeration of Heat-Treated Probiotics in Functional Beverages
· Journal of AOAC International
2026 META_ANALYSIS
The Efficacy of Probiotics in Treating Upper Respiratory Tract Infections, Allergic Rhinitis, and Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis
· Microorganisms
2026 REVIEW
Insights into next-generation encapsulation of probiotics from a benchmark strain perspective
· LWT
2026 IN_VITRO
Potential of guava pulps treated by ohmic heating as a delivery vehicle for probiotic bacteria: stability, functional properties, and in vitro digestibility
· International Journal of Food Microbiology
2026 RCT
Intravesical Lacticaseicillus rhamnosus GG reduces symptoms among people with spinal cord injury and disease who use intermittent catheterization: A randomized comparison of two- and four-dose regimens
· medRxiv
2026 IN_VITRO
Substrate transport limits phenylalanine ammonia-lyase activity in engineered Lacticaseibacillus rhamnosus GG
· bioRxiv (Cold Spring Harbor Laboratory)
2026 IN_VITRO
New Postbiotic Deriving from Sequential Fermentation of Two Lacticaseibacillus Strains Exerts Beneficial Effects on Epithelial Gut Barrier and Innate Immunity in Human Enterocytes
· Preprints.org
2026 OTHER
New Insights into Probiotic Enumeration in a Complex Food Matrix: Flow Cytometry and Plate Count Correlation
· Journal of AOAC International
2026 IN_VITRO
New Postbiotic Derived from Sequential Fermentation of Two Lacticaseibacillus Strains Exerts Beneficial Effects on Epithelial Gut Barrier and Innate Immunity in Human Enterocytes
· Microorganisms
2026 IN_VITRO
Hollow-core wood hemicellulose-based microcapsules entrap probiotics within protective walls
· Journal of Colloid and Interface Science
2026 ANIMAL
Evaluation of the Antifungal Effect of Lacticaseibacillus rhamnosus GG against Oral candidiasis in Healthy Sprague-Dawley Rats
· Journal of Genetic Engineering and Biotechnology
2026 META_ANALYSIS
Impact of Probiotics on Children with Acute Gastroenteritis: Results from an Umbrella Meta-Analysis
· Journal of Integrative and Complementary Medicine
2026 OTHER
Enhanced antitumor efficacy of sulfasalazine and mesalazine in colorectal cancer through modulatory action of Lacticaseibacillus rhamnosus GG
· Naunyn-Schmiedeberg s Archives of Pharmacology
2026 ANIMAL
Production and Characterization of Potentially Symbiotic Acerola Ice Cream with Partially Hydrolyzed Guar Gum and Added Lacticaseibacillus rhamnosus GG
· Foods
Browse all 3,593 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Comparison of Two Active Doses of Microencapsulated Lacticaseibacillus rhamnosus GG in a Yoghurt Drink on Gut Microbiome Profiles in Healthy Adults: A Randomised, Double-Blind Crossover Trial
    · Bacteria · 2026
    Source →
  2. [2]
    New Postbiotic Derived from Sequential Fermentation of Two Lacticaseibacillus Strains Exerts Beneficial Effects on Epithelial Gut Barrier and Innate Immunity in Human Enterocytes
    · Microorganisms · 2026
    PMID 42075327 →
  3. [3]
    Insights into next-generation encapsulation of probiotics from a benchmark strain perspective
    · LWT · 2026
    Source →
  4. [4]
    Impact of Probiotics on Children with Acute Gastroenteritis: Results from an Umbrella Meta-Analysis
    · Journal of Integrative and Complementary Medicine · 2026
    PMID 42080229 →
  5. [5]
    The Assessment of Multidimensional Clinical, Biological and Patient-Reported Outcomes to Evaluate the Efficacy of Add-On Lactobacillus rhamnosus GG Supplementation in Mild Ulcerative Colitis: A Randomized Pilot Trial
    · Nutrients · 2026
    PMID 42123931 →
  6. [6]
    Exploring the immune modulatory effects of probiotics in autoimmune diseases
    · International Journal of Immunology Research · 2026
    Source →
  7. [7]
    Maternal immune activation perturbs intestinal niche through microbial glycerophospholipids and drives offspring behavioral abnormalities
    · Cell Reports · 2026
    PMID 41926285 →
  8. [8]
    Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus
    · Advanced Science · 2026
    PMID 41717712 →
  9. [9]
    The impact of probiotics on gut health and immune system modulation: A comprehensive study
    · Journal of Advances in Microbiology Research · 2026
    Source →
  10. [10]
    Effects of UDCA and probiotics on metabolic outcomes in type 2 diabetes patients on metformin: A randomized trial in Bosnia and Herzegovina
    · Technology and Health Care · 2026
    PMID 42033401 →