Lacticaseibacillus rhamnosus GG
Lacticaseibacillus rhamnosus GG (LGG) is one of the most extensively studied probiotic strains globally, though the papers linked to this strain entry focus primarily on encapsulation technology and formulation stability rather than clinical efficacy — examining how LGG survives in foods like apple juice, yogurt, and chocolate. In vitro studies have examined LGG's interactions with the gut microbiome during antibiotic exposure and activity against certain pathogenic bacteria. The broader LGG literature, not captured in this strain's linked papers, includes numerous human clinical trials across digestive and immune outcomes; strain-specific summaries here are grounded only in the indexed evidence, which is largely formulation-focused. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 2,224 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 888 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+17 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
3593 papers reference this strain in the probiotic database.
Discussion
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Citations
Selected papers that name this strain.
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[1]
Source →Comparison of Two Active Doses of Microencapsulated Lacticaseibacillus rhamnosus GG in a Yoghurt Drink on Gut Microbiome Profiles in Healthy Adults: A Randomised, Double-Blind Crossover Trial· Bacteria · 2026
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[2]
PMID 42075327 →New Postbiotic Derived from Sequential Fermentation of Two Lacticaseibacillus Strains Exerts Beneficial Effects on Epithelial Gut Barrier and Innate Immunity in Human Enterocytes· Microorganisms · 2026
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[3]
Source →Insights into next-generation encapsulation of probiotics from a benchmark strain perspective· LWT · 2026
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[4]
PMID 42080229 →Impact of Probiotics on Children with Acute Gastroenteritis: Results from an Umbrella Meta-Analysis· Journal of Integrative and Complementary Medicine · 2026
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[5]
PMID 42123931 →The Assessment of Multidimensional Clinical, Biological and Patient-Reported Outcomes to Evaluate the Efficacy of Add-On Lactobacillus rhamnosus GG Supplementation in Mild Ulcerative Colitis: A Randomized Pilot Trial· Nutrients · 2026
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[6]
Source →Exploring the immune modulatory effects of probiotics in autoimmune diseases· International Journal of Immunology Research · 2026
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[7]
PMID 41926285 →Maternal immune activation perturbs intestinal niche through microbial glycerophospholipids and drives offspring behavioral abnormalities· Cell Reports · 2026
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[8]
PMID 41717712 →Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus· Advanced Science · 2026
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[9]
Source →The impact of probiotics on gut health and immune system modulation: A comprehensive study· Journal of Advances in Microbiology Research · 2026
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[10]
PMID 42033401 →Effects of UDCA and probiotics on metabolic outcomes in type 2 diabetes patients on metformin: A randomized trial in Bosnia and Herzegovina· Technology and Health Care · 2026