Strain Profile
· NCBI Strain Taxon
568703
NCBI Taxonomy's node for this specific strain. A different identifier from the culture-collection deposit numbers below, which name a physical stock rather than a taxonomic node.
How we classify this →
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Lacticaseibacillus rhamnosus GG
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lacticaseibacillus rhamnosus GG (LGG) is one of the most extensively studied probiotic strains globally, though the papers linked to this strain entry focus primarily on encapsulation technology and formulation stability rather than clinical efficacy — examining how LGG survives in foods like apple juice, yogurt, and chocolate. In vitro studies have examined LGG's interactions with the gut microbiome during antibiotic exposure and activity against certain pathogenic bacteria. The broader LGG literature, not captured in this strain's linked papers, includes numerous human clinical trials across digestive and immune outcomes; strain-specific summaries here are grounded only in the indexed evidence, which is largely formulation-focused. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 2,266 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 902 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+17 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
3679 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
OTHER
OTHER
IN_VITRO
2026
IN_VITRO
2026
IN_VITRO
2026
IN_VITRO
2026
RCT
2026
REVIEW
2026
IN_VITRO
2026
RCT
2026
IN_VITRO
2026
ANIMAL
2026
RCT
2026
ANIMAL
2026
IN_VITRO
2026
OTHER
2026
IN_VITRO
2026
ANIMAL
2026
META_ANALYSIS
2026
WGS
Browse all 3,679 papers →
Integrazione di approcci omici per la caratterizzazione di batteri intestinali chiave: dalla modulazione della comunita microbica all’analisi funzionale del singolo ceppo
· IRIS UNIMORE (University of Modena and Reggio Emilia)
Development of a Frozen Meat Semi-Finished Product with the Probiotic Culture Lacticaseibacillus rhamnosus GG
Разработка замороженного мясного полуфабриката с пробиотической культурой Lacticaseibacillus rhamnosus GG
· CyberLeninK (CyberLeninka)
Should the drug resistance of probiotic strains be extrapolated and should it be based on species or the given strain with regards to 5th generation cephalosporins?
· Jagiellonian University Repository (Jagiellonian University)
Biosynthesis of Magnetite Nanoparticles Mediated by Chia Mucilage and Its Co-Encapsulation with Lactobacillus rhamnosus GG by Spray Drying: Evaluation Under Simulated Gastrointestinal Digestion
· Foods
Simulasi In Silico Integrasi EGF ke Lactobacillus rhamnosus GG melalui CRISPR-Cas9 Sebagai Probiotik Terapeutik Ulkus Kronis
· Jurnal Ilmiah Pangan Halal
Tryptophan-enriched Lactobacillus rhamnosus GG-derived Nanovesicles Promote Alveolar Bone Regeneration Through Macrophage Fatty Acid Oxidation
· Biomaterials Research
A double blind RCT to examine the safety and efficacy of Lactobacillus rhamnosus GG in pediatric febrile neutropenia
· Blood Global Hematology
Lesion of the Urinary Bladder Microbiome in Neurogenic Dysfunction after Spinal Cord Injury
· Zenodo (CERN European Organization for Nuclear Research)
Structure-activity relationship of Laminaria japonica polysaccharide in promoting acetic acid synthesis by Lactobacillus rhamnosus GG
· Food Research International
Efficacy of Lactobacillus Rhamnosus GG add-on therapy in mild-to-moderate ulcerative colitis
· http://isrctn.com/
High molecular-weight polysaccharide contamination from yeast extract in semi-defined bacteriological media: Effects on exopolysaccharide production and purity
· bioRxiv (Cold Spring Harbor Laboratory)
INFLUENCE OF BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS BB-12 AND LACTOBACILLUS RHAMNOSUS GG ON POLARIZATION OF TUMOR-ASSOCIATED MACROPHAGES
· Experimental Oncology
Lactobacillus rhamnosus GG to Reduce Necrotising Enterocolitis, Sepsis, and Mortality in Very Low Birth Weight Infants: A Randomized Controlled Trial
· Indian Pediatrics
Lactobacillus rhamnosus GG mitigates bone loss induced by mechanical unloading via regulation of the gut-bone axis
· Frontiers in Nutrition
Study of the prebiotic potential of Punica granatum (Pomegranate) flower extract on the bioactivity of probiotic strains
· Research Journal of Biotechnology
Cost Analysis of Prepared Synbiotic Banana Lassi Enriched with Honey and L. rhamnosus GG
· Open MIND
Integrating microbial genomics and neurotranscriptomics to understand the impact of probiotic strains on neurological health
· Frontiers in Cellular and Infection Microbiology
Lactobacillus rhamnosus GG Alleviates Post-Weaning Stress-Induced Intestinal Barrier Damage and Inflammation by Promoting Intestinal Health and Modulating the Gut Microbiota in Piglets
· Microorganisms
Comparative efficacy of probiotic, prebiotic, and synbiotic interventions in children with functional abdominal pain disorders: a systematic review and network meta-analysis
· Frontiers in Nutrition
Probiotic potential and genomic insights of Companilactobacillus farinae sp. nov. from Thai fermented rice flour for functional food application
· SSRN Electronic Journal
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 42075327 →New Postbiotic Derived from Sequential Fermentation of Two Lacticaseibacillus Strains Exerts Beneficial Effects on Epithelial Gut Barrier and Innate Immunity in Human Enterocytes· Microorganisms · 2026
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[2]
Source →Insights into next-generation encapsulation of probiotics from a benchmark strain perspective· LWT · 2026
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[3]
PMID 42080229 →Impact of Probiotics on Children with Acute Gastroenteritis: Results from an Umbrella Meta-Analysis· Journal of Integrative and Complementary Medicine · 2026
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[4]
PMID 42123931 →The Assessment of Multidimensional Clinical, Biological and Patient-Reported Outcomes to Evaluate the Efficacy of Add-On Lactobacillus rhamnosus GG Supplementation in Mild Ulcerative Colitis: A Randomized Pilot Trial· Nutrients · 2026
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[5]
Source →Exploring the immune modulatory effects of probiotics in autoimmune diseases· International Journal of Immunology Research · 2026
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[6]
PMID 41926285 →Maternal immune activation perturbs intestinal niche through microbial glycerophospholipids and drives offspring behavioral abnormalities· Cell Reports · 2026
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[7]
PMID 41717712 →Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus· Advanced Science · 2026
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[8]
Source →The impact of probiotics on gut health and immune system modulation: A comprehensive study· Journal of Advances in Microbiology Research · 2026
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[9]
PMID 42033401 →Effects of UDCA and probiotics on metabolic outcomes in type 2 diabetes patients on metformin: A randomized trial in Bosnia and Herzegovina· Technology and Health Care · 2026
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[10]
Source →Comparison of Two Active Doses of Microencapsulated Lacticaseibacillus rhamnosus GG in a Yoghurt Drink on Gut Microbiome Profiles in Healthy Adults: A Randomised, Double-Blind Crossover Trial· Bacteria · 2026