Strain Profile · NCBI Species Taxon 47715
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Lacticaseibacillus rhamnosus

◐ Food-origin
Sequenced
Public genome assembly available

Lacticaseibacillus rhamnosus, most widely studied as the GG strain, has an extensive research record, though the evidence base in this index is predominantly in vitro and animal-model work. Laboratory studies have examined intestinal barrier integrity and antimicrobial activity against certain pathogens, including mechanisms such as bioactive peptides and pilus-mediated adhesion. A 2022 scoping review examined supplementation effects on children's health across food and non-food delivery formats. The broader clinical picture remains early-stage, and findings from cell and animal studies do not establish proven human health outcomes. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 2,746 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+6 more systems

Symptoms in the research

Share of this strain's 1,066 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+17 more symptoms

Strains of this species

20 strains of Lacticaseibacillus rhamnosus in the index, with 4,269 linked papers between them.

Lacticaseibacillus rhamnosus MTCC 5462

MTCC 5462

Lacticaseibacillus rhamnosus MTCC 5462 is an Indian deposited strain whose published research base is composed entirely of in vitro and genomic studies.

Survival Metabolic Adhesion
◐ Food-origin
13 papers 0 comments

Lacticaseibacillus rhamnosus GG

™ GG
ATCC 53103

Lacticaseibacillus rhamnosus GG (LGG) is one of the most extensively studied probiotic strains globally, though the papers linked to this strain entry focus primarily on encapsulation technology and formulation stability…

Barrier Immune Survival
◐ Food-origin
3679 papers 0 comments

Lacticaseibacillus rhamnosus HN001

™ HN001

Lacticaseibacillus rhamnosus HN001 (formerly classified as Lactobacillus rhamnosus HN001) has been studied across in vitro, animal, and human randomized controlled trial settings.

Immune Metabolic Barrier
◐ Food-origin
216 papers 0 comments

Lacticaseibacillus rhamnosus R0011

™ R0011

Lacticaseibacillus rhamnosus R0011 is a well-studied probiotic strain with a research base spanning food technology, immunology, and gut health.

Barrier Immune Adhesion
◐ Food-origin
89 papers 0 comments

Lacticaseibacillus rhamnosus Lcr35

™ Lcr35

Lacticaseibacillus rhamnosus Lcr35 (formerly Lactobacillus casei rhamnosus Lcr35) has been evaluated in several randomized controlled trials across distinct clinical contexts, including pediatric chronic constipation, va…

Immune Adhesion Survival
◐ Food-origin
71 papers 0 comments

Lacticaseibacillus rhamnosus GR-1

™ GR-1

Lacticaseibacillus rhamnosus GR-1 is among the most thoroughly researched probiotic strains for urogenital health, with multiple randomized controlled trials evaluating its oral use in relation to vaginal microbiota comp…

Precision Adhesion Immune
◐ Food-origin
88 papers 0 comments

Lacticaseibacillus rhamnosus Lr-32

™ Lr-32

Lacticaseibacillus rhamnosus LR-32 appears in the indexed literature primarily as a component of multi-strain probiotic formulations.

Adhesion Immune Survival
◐ Food-origin
16 papers 0 comments

Lacticaseibacillus rhamnosus LRa05

™ LRa05

Lacticaseibacillus rhamnosus LRa05 is an emerging probiotic strain with a growing evidence base spanning animal models and several randomized controlled trials.

Barrier Metabolic Adhesion
◐ Food-origin
25 papers 0 comments

Lacticaseibacillus rhamnosus LRH10

™ LRH10

Lacticaseibacillus rhamnosus LRH10 is a strain of L.

◐ Food-origin
0 papers 0 comments

Lacticaseibacillus rhamnosus LB21

™ LB21

Lacticaseibacillus rhamnosus LB21 is a strain with a modest body of published research, primarily focused on oral microbiome interactions.

Precision Adhesion AMR & toxins
◐ Food-origin
6 papers 0 comments

Lacticaseibacillus rhamnosus DSM 14870

DSM 14870

Lacticaseibacillus rhamnosus DSM 14870 (also known as L.

Metabolic Adhesion AMR & toxins
◐ Food-origin
9 papers 0 comments

Lacticaseibacillus rhamnosus PB01

™ PB01

Lacticaseibacillus rhamnosus PB01 is a lactic acid bacterium studied for its antimicrobial and metabolic properties.

Immune Metabolic Precision
◐ Food-origin
6 papers 0 comments

Lacticaseibacillus rhamnosus LR06

™ LR06

Lacticaseibacillus rhamnosus LR06 appears primarily as a component of multi-strain probiotic formulations, where it has been studied alongside other bacterial species in randomized controlled trials.

Metabolic Barrier Immune
◐ Food-origin
15 papers 0 comments

Lacticaseibacillus rhamnosus LOCK0900

™ LOCK0900

Lacticaseibacillus rhamnosus LOCK0900 (formerly Lactobacillus rhamnosus LOCK900) is a strain that has been explored for use in fermented meat products and studied in vitro for its potential effects on intestinal epitheli…

Adhesion Immune Barrier
◐ Food-origin
3 papers 0 comments

Lacticaseibacillus rhamnosus SP1

™ SP1

Lacticaseibacillus rhamnosus SP1 has been studied in multiple randomized controlled trials with a notable focus on oral health.

Barrier Adhesion Precision
◐ Food-origin
10 papers 0 comments

Lacticaseibacillus rhamnosus CNCM I-4036

™ CNCM I-4036

Lacticaseibacillus rhamnosus CNCM I-4036 was originally isolated from the feces of exclusively breastfed infants and has since been studied alongside two companion strains (L.

Immune Barrier Metabolic
◐ Food-origin
16 papers 0 comments

Lacticaseibacillus rhamnosus CECT 8361

CECT 8361

Lacticaseibacillus rhamnosus CECT 8361 has a modest research base, with evidence drawn from two randomized controlled trials in which it was used as part of a multi-strain formulation.

Barrier Immune Metabolic
◐ Food-origin
4 papers 0 comments

Lacticaseibacillus rhamnosus CECT 8362

CECT 8362

Lacticaseibacillus rhamnosus CECT 8362 is a strain of the well-studied rhamnosus species deposited in the Spanish Type Culture Collection (CECT).

◐ Food-origin
0 papers 0 comments

Lacticaseibacillus rhamnosus LR

DEP LR

Lacticaseibacillus rhamnosus LR appears in a range of in vitro and animal studies spanning oral health, gut barrier function, and metabolic research, areas consistent with the broader L.

Immune Survival Metabolic
◐ Food-origin
58 papers 0 comments

Lacticaseibacillus rhamnosus UCO-25A

DEP UCO-25A

Lacticaseibacillus rhamnosus UCO-25A is a lactic acid bacterium isolated from human gastric sources.

Barrier Immune Adhesion
◐ Food-origin
4 papers 0 comments

Research

5597 papers reference this strain in the probiotic database.

Match confidence
OTHER
Development of a Frozen Meat Semi-Finished Product with the Probiotic Culture Lacticaseibacillus rhamnosus GG
Разработка замороженного мясного полуфабриката с пробиотической культурой Lacticaseibacillus rhamnosus GG
· CyberLeninK (CyberLeninka)
IN_VITRO
Studies on the Effects of Probiotics and Various Immunostimulatory Agents: Investigation of Infection Defense Mechanisms Using Leukocyte Dynamics in a Salmonella-Infected Rat Model
プロバイオティクスおよび各種免疫賦活物質の効果に関する研究 : サルモネラ感染モデルラットの白血球動態を指標にした感染防御機構の検討
· Institutional Repositories DataBase (IRDB)
OTHER
Biochemical studies on potential probiotic strains of Lactobacillus rhamnosus isolated from fermented Sumbawa mare's milk
· Institutional Repositories DataBase (IRDB)
IN_VITRO
Should the drug resistance of probiotic strains be extrapolated and should it be based on species or the given strain with regards to 5th generation cephalosporins?
· Jagiellonian University Repository (Jagiellonian University)
2026 ANIMAL
Evaluating the efficacy of postbiotics derived from Lactobacillus spp. on growth performance in broiler
· Ciência e Agrotecnologia
2026 ANIMAL
Investigating the Effects of Heat-Killed Cell-Free Supernatant of Lactobacillus rhamnosus on Murine Melanoma Cells and Animal Models
· Journal of Pharmaceutical Innovation
2026 WGS
Figure 1. Circular chromosome map of L. rhamnosus B7-1-12
· Figshare
2026 OTHER
Intratracheal Lactobacillus rhamnosus attenuates poultry-house PM2.5-induced lung inflammation in broilers by remodeling the pulmonary microbiota–metabolite axis
· Environmental Pollution
2026 IN_VITRO
Enhancing the physicochemical, microbiological, sensory, and functional properties of reduced-lactose probiotic fermented milk beverages via paraprobiotic supplementation
· European Food Research and Technology
2026 OTHER
Table 3. Summary of COGs for for L. rhamnosus B34-0-2
· Figshare
2026 ANIMAL
Lactobacillus rhamnosus GG Alleviates Post-Weaning Stress-Induced Intestinal Barrier Damage and Inflammation by Promoting Intestinal Health and Modulating the Gut Microbiota in Piglets
· Microorganisms
2026 ANIMAL
In vivo tracking and survival analysis of lactobacillus strains using fluorescent d-amino acids
· Food Science and Biotechnology
2026 WGS
Fig 1. Circular chromosome map of L. rhamnosus B7-1-12
· Figshare
2026 OTHER
Development of Technology for Lyophilized Starter Cultures of Mesophilic Lactobacilli
Разработка технологии лиофилизированных заквасок мезофильных лактобацилл
· Food processing industry
2026 OTHER
Probiotic‐Derived CpG ‐ DNA Enhances Food Allergy Immunotherapy via TLR9‐Dependent Breg Induction and IL ‐10 Epigenetic Activation
· Clinical & Experimental Allergy
2026 WGS
Oral Lactobacillus rhamnosus Is associated with pancreatic tumor growth and reduced T-Cell infiltration in mice
· Current Proteomics
2026 OTHER
ROLE OF LACTOBACILLUS RHAMNOSUS PROBIOTIC IN THE TREATMENT AND PREVENTION OF RECURRENCE OF BACTERIAL VAGINOSIS
· Zenodo (CERN European Organization for Nuclear Research)
2026 ANIMAL
Therapeutic effects of Lactobacillus rhamnosus, thymol and their combination against neurotoxicity in propionic acid (PA)-induced autistic rats: insights into the role of the Nrf2/HO-1, Wnt3/β-catenin/GSK3β BDNF/p-TrkB/CREB, pI3K/Akt/mTOR, AMPK/SIRT-1, and PERK/CHOP/Bcl-2 pathways
· Frontiers in Pharmacology
2026 ANIMAL
Comprehensive 16S rRNA Sequencing and Untargeted Metabolomics Analysis Reveal the Mechanism of Oral Microorganisms in Rat Dental Caries
· Discovery Medicine
2026 IN_VITRO
Assessment of molecular interactions and anti-inflammatory activity of fermented camel milk-derived peptides in RAW macrophages
· Amino Acids
Browse all 5,597 papers →

Discussion

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Citations

Selected papers that name this strain.

  1. [1]
    ROLE OF LACTOBACILLUS RHAMNOSUS PROBIOTIC IN THE TREATMENT AND PREVENTION OF RECURRENCE OF BACTERIAL VAGINOSIS
    · Zenodo (CERN European Organization for Nuclear Research) · 2026
    Source →
  2. [2]
    Randomized, Double-Blind, Placebo-Controlled Clinical Trial Assessing the Efficacy of Lacticaseibacillus rhamnosus CRL 1505 in Preventing Upper Respiratory Tract Infections in Healthy Adults
    · Microorganisms · 2026
    Source →
  3. [3]
    Probiotics Augment the Effect of Non‐Surgical Periodontal Treatment—A Randomised, Double‐Blinded, Placebo‐Controlled Trial
    · Journal Of Clinical Periodontology · 2026
    PMID 42076937 →
  4. [4]
    Multi‐Strain Probiotics BLa80, LRa05, and BBr60 Modulate Inflammation, Bile Acids, and Gut Microbiota in Type 2 Diabetes: A Randomized Controlled Trial
    · Food Science & Nutrition · 2026
    PMID 41971606 →
  5. [5]
    Impact of Probiotics on Children with Acute Gastroenteritis: Results from an Umbrella Meta-Analysis
    · Journal of Integrative and Complementary Medicine · 2026
    PMID 42080229 →
  6. [6]
    Probiotici u pedijatrijskoj gastroenterologiji
    · Paediatria Croatica · 2026
    Source →
  7. [7]
    Probiotics in the alleviation of food allergies in infants and young children: research progress
    · Critical Reviews in Food Science and Nutrition · 2026
    PMID 42138226 →
  8. [8]
    Current Treatment Strategies and Effectiveness of Adjunct Therapy in the Treatment of Recurrent Bacterial Vaginosis
    · Digital Showcase Research, Scholarship, & Creative Works (University of Lynchburg) · 2026
    Source →
  9. [9]
    Improving Lipid Profiles Through Lactobacillus rhamnosus Supplementation in Dyslipidemic Animal Models: A Systematic Review and Meta-Analysis
    · Foods · 2026
    PMID 41683053 →
  10. [10]
    Augmenting Cognitive Function in the Elderly with Mild Cognitive Impairment Using Probiotic Lacticaseibacillus rhamnosus CBT-LR5: A 12-Week Randomized, Double-Blind, Parallel-Group Non-Comparative Study
    · Nutrients · 2025
    PMID 40005019 →