Strain Profile
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Lactobacillus fermentum
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Food-origin
Where this strain was first isolated, curated from the literature and culture-collection catalogs. It describes provenance only — not suitability, and not benefit.
How we classify this →
Sequenced
Whether a public genome assembly is linked for this strain. Without one the genome screens cannot run. It is not a verdict on the organism.
How we classify this →
Public genome assembly available
Lactobacillus fermentum (species-level entry, no specific strain designation) is a heterofermentative lactic acid bacterium found in fermented foods and the human gastrointestinal tract. The linked literature spans in vitro characterization of probiotic properties, antioxidant activity examined in vitro and in animal models, bacteriocin production, surface protein characterization, and a pharmacokinetic study tracking gastrointestinal transit in humans. Health efficacy conclusions are strain-dependent, and the linked papers do not converge on a single isolate with a defined clinical profile. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.
Where it's been studied Tags come from a conservative keyword scan of each paper's title, abstract, and summary. A tag is research coverage, not measured effect. How we classify this →
Share of this strain's 366 body-system-tagged papers that concern each system. Research coverage, not measured effect.
Symptoms in the research A tag means the paper's text names the symptom or condition — research coverage, not evidence of benefit. How we classify this →
Share of this strain's 144 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.
+14 more symptoms
Research Study-type filters use AI-classified labels, audited but not guaranteed — check the paper itself before leaning on one. How we classify this →
648 papers reference this strain in the probiotic database.
Match confidence
How strongly this paper was matched to this strain when the corpus was linked. It orders the list — it says nothing about the study's quality or its findings.
How we classify this →
2025
ANIMAL
2025
ANIMAL
2025
ANIMAL
2024
ANIMAL
2024
REVIEW
2024
IN_VITRO
2024
IN_VITRO
2024
OTHER
2023
ANIMAL
2023
ANIMAL
2023
ANIMAL
2023
IN_VITRO
2023
ANIMAL
2023
ANIMAL
2023
OTHER
2023
IN_VITRO
2023
OTHER
2023
ANIMAL
2023
ANIMAL
2023
RCT
Browse all 648 papers →
Encapsulation of L. fermentum with chitosan-alginate enhances its bioactivity against acrylamide toxicity in D.mel
· Scientific Reports
Lactobacillus fermentum 016 Alleviates Mice Colitis by Modulating Oxidative Stress, Gut Microbiota, and Microbial Metabolism
· Nutrients
Melanin nanoparticles-loaded lactobacillus fermentum exosomes for targeted and visualized treatment of ulcerative colitis
· Journal of Advanced Research
Inhibition and Mechanism of Protein Nonenzymatic Glycation by Lactobacillus fermentum
· Foods
Limosilactobacillus fermentum Strains as Novel Probiotic Candidates to Promote Host Health Benefits and Development of Biotherapeutics: A Comprehensive Review
· Probiotics and Antimicrobial Proteins
Postbiotic metabolites derived from lactobacillus fermentum as potent antiproliferative bioresources on HeLa cells with promising biocompatibility
· BMC Complementary Medicine and Therapies
Probiotic Characteristics and Anti-Inflammatory Effects of Limosilactobacillus fermentum 664 Isolated from Chinese Fermented Pickles
· Antioxidants
Inoculation fermentation with Lactobacillus fermentum L28 and Staphylococcus epidermidis S24 for improving the protein degradation of air-dried goose
· Food Chemistry
Lactobacillus fermentum Alleviates the Colorectal Inflammation Induced by Low-Dose Sub-Chronic Microcystin-LR Exposure
· Toxins
NF-kB Regulation and the Chaperone System Mediate Restorative Effects of the Probiotic Lactobacillus fermentum LF31 in the Small Intestine and Cerebellum of Mice with Ethanol-Induced Damage
· Biology
Lactobacillus fermentum HY7302 Improves Dry Eye Symptoms in a Mouse Model of Benzalkonium Chloride-Induced Eye Dysfunction and Human Conjunctiva Epithelial Cells
· International Journal of Molecular Sciences
Electrospinning Microencapsulation of Lactobacillus fermentum K73 Using Gelatin as the Main Component of a Food-Grade Matrix
· Microorganisms
Biosorption of Cd+2 and Pb+2 by Exopolysaccharide Extracted from Lactobacillus fermentum 6b; Adsorption Isotherm and Kinetic Studies
· Iranian Journal of Public Health
Lactobacillus fermentum HNU312 alleviated oxidative damage and behavioural abnormalities during brain development in early life induced by chronic lead exposure
· Ecotoxicology and Environmental Safety
Fermentation of Lactobacillus fermentum NB02 with feruloyl esterase production increases the phenolic compounds content and antioxidant properties of oat bran
· Food Chemistry
Effects of Lactobacillus fermentum GD01 fermentation on the nutritional components and flavor substances of three kinds of bean milk
· LWT
Effect of Malva neglecta and lactulose on survival of Lactobacillus fermentum and textural properties of synbiotic stirred yogurt
· Journal of Food Science and Technology
Lactobacillus fermentum F40-4 ameliorates hyperuricemia by modulating the gut microbiota and alleviating inflammation in mice
· Food & Function
Exopolysaccharide is the potential effector of Lactobacillus fermentum PS150, a hypnotic psychobiotic strain
· Frontiers in Microbiology
Effects of Lactobacillus fermentum Administration on Intestinal Morphometry and Antibody Serum Levels in Salmonella-Infantis-Challenged Chickens
· Microorganisms
Discussion
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Citations
Selected papers that name this strain.
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[1]
PMID 38393628 →Limosilactobacillus fermentum Strains as Novel Probiotic Candidates to Promote Host Health Benefits and Development of Biotherapeutics: A Comprehensive Review· Probiotics and Antimicrobial Proteins · 2024
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[2]
PMID 36529865 →Effect of Lactobacillus Fermentum as a Probiotic Agent on Bone Health in Postmenopausal Women· Journal of Bone Metabolism · 2022
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[3]
PMID 34251007 →Effect of Lactobacillus fermentum TKSN041 on improving streptozotocin-induced type 2 diabetes in rats· Food & Function · 2021
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[4]
PMID 32216468 →Effects of Lactobacillus fermentum CECT5716 Lc40 on infant growth and health: a randomised clinical trial in nursing women· Beneficial Microbes · 2020
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[5]
PMID 31630683 →Evaluation of the safety, tolerance and efficacy of 1-year consumption of infant formula supplemented with Lactobacillus fermentum CECT5716 Lc40 or Bifidobacterium breve CECT7263: a randomized controlled trial· BMC Pediatrics · 2019
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[6]
PMID 31729242 →Lactobacillus fermentum: a bacterial species with potential for food preservation and biomedical applications· Critical Reviews in Food Science and Nutrition · 2019
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[7]
Source →Oral Administration to Nursing Women of Lactobacillus fermentum CECT5716 Prevents Lactational Mastitis Development: A Randomized Controlled Trial· Breastfeeding Medicine · 2017
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[8]
PMID 26352805 →Lactobacillus fermentum CECT 5716 Reduces Staphylococcus Load in the Breastmilk of Lactating Mothers Suffering Breast Pain: A Randomized Controlled Trial· Breastfeeding Medicine · 2015
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[9]
Source →Regulation of plasma lipid profile by lactobacillus fermentum (probiotic strain ME-3 DSM14241) in a randomised controlled trial of clinically healthy adults· BMC Nutrition · 2015
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[10]
PMID 25697549 →Long-term safety of early consumption of Lactobacillus fermentum CECT5716: A 3-year follow-up of a randomized controlled trial· Pharmacological Research · 2015