Strain Profile
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Lactobacillus brevis

◐ Food-origin
Sequenced
Public genome assembly available

Lactobacillus brevis is a heterofermentative lactic acid bacterium widely distributed in fermented food environments. Research has examined the strain's functional properties including antimicrobial activity, fermentation characteristics, and potential probiotic mechanisms. In vitro and animal studies have examined possible roles in fermentation and gut health, though human clinical evidence remains limited. The strain has been evaluated for safety in food production. These are research topics, not findings; the papers do not establish that this strain treats or prevents any condition.

Where it's been studied

Share of this strain's 1,028 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+6 more systems

Symptoms in the research

Share of this strain's 296 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+17 more symptoms

Research

4899 papers reference this strain in the probiotic database.

Match confidence
ANIMAL
Heat‐killed Lactobacillus brevis KB290 attenuates visceral fat accumulation induced by high‐fat diet in mice
· Institutional Repositories DataBase (IRDB)
2026 OTHER
Synthetic galactooligosaccharides and milk protein conjugates enhance the prebiotic efficacy for Levilactobacillus brevis
· SSRN Electronic Journal
2026 IN_VITRO
Chive-Fortified Fermentation Enhances Gamma-Aminobutyric Acid Production by Levilactobacillus brevis PL9014
· International Journal of Probiotics and Prebiotics
2026 ANIMAL
Systems-level investigation of the anxiolytic gut–brain interactions induced by paraprobiotic Lactobacillus brevis SBC8803 in zebrafish
· Frontiers in Microbiology
2026 IN_VITRO
Biosynthesis of CuO-ZnO nanoparticles using Levilactobacillus brevis: implication in antibacterial, antioxidant, and anticancer activities
· Scientific Reports
2026 IN_VITRO
Intestinal Epithelial-like Cells Stimulated by a Functional Food Ingredient Promote Lysyl Oxidase (LOX) Expression in Osteoblast Precursor Cells via BMP-1 Secretion
· International Journal of Molecular Sciences
2026 ANIMAL
Synergistic dietary supplements of Lactobacillus brevis and trans-cinnamic acid improved growth, immune response, and disease resistance in common carp
· Scientific Reports
2026 IN_VITRO
The novel autochthonous probiotic strain Lactobacillus brevis BGZLS30-24 improves the functional characteristics of Khorasan wheat sourdough bread
· Applied Food Research
2026 IN_VITRO
RSM-optimized co-encapsulation of Lactobacillus brevis LSe and FOS in calcium alginate: enhancing encapsulation efficiency and bacterial growth
· BMC Microbiology
2026 IN_VITRO
Effects of Sequential Fermentation with Saccharomyces bayanus and Lactobacillus brevis on the Metabolite Composition and Antioxidant Activity of Chinese Yam Juice
· Foods
2026 IN_VITRO
Viability of Lactobacillus brevis isolated from Riau Dadih in a microencapsulated matrix based on Avicel 102 microcrystalline cellulose and skim milk
· IOP Conference Series Earth and Environmental Science
2026 OTHER
Lactobacillus brevis Cell-Free Supernatant Recalibrates TLR-Mediated Inflammatory Signaling While Preserving Immune Competence in HT-29 Intestinal Epithelial Cells
· Research Square
2026 ANIMAL
Enhancing Effects of Lactobacillus brevis CQPC12 on Antibiotic-Induced Motor Dysfunction in Mice
·
2026 OTHER
Sequential fermentation with Saccharomyces cerevisiae, Levilactobacillus brevis and Acetobacter pasteurianus for GABA-enriched low-alcohol functional beverages: Optimization and synergistic formation mechanism of GABA
· SSRN Electronic Journal
2026 ANIMAL
Systems-level Investigation of the Anxiolytic Gut–Brain Interactions induced by Paraprobiotic Lactobacillus brevis SBC8803 in Zebrafish
· bioRxiv (Cold Spring Harbor Laboratory)
2026 RCT
Effects of GABA-enriched rice germ extract fermented by Lactobacillus brevis BJ20 on stress symptoms and related biomarkers in adults: a randomized, double-blind, placebo-controlled trial
· Journal of Functional Foods
2026 IN_VITRO
The Therapeutic Administration of Lactobacillus brevis ZG2488 Suppresses Influenza A Virus Replication Through a Viability-Dependent Host Transcriptional Modulation Mechanism
· Microorganisms
2026 IN_VITRO
SHELF-LIFE ANALYSIS OF POTATO MILK AND POTATO YOGURT STORED AT DIFFERENT TEMPERATURES AND VIABILITY OF Lactobacillus brevis IN POTATO YOGURT
· Journal of Microbiology Biotechnology and Food Sciences
2026 OTHER
Characterization and antibacterial activity of a Bacteriocin-like Inhibitory Substance (BLIS) produced by Levilactobacillus brevis
· Brazilian Journal of Microbiology
2026 IN_VITRO
Unveiling the molecular secrets: How Levilactobacillus brevis PDD-5 lowers uric acid levels
· Food Science and Human Wellness
Browse all 4,899 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Inhibitory Effect of Levilactobacillus brevis on Salivary α‐Amylase: Evidence From In Vivo and In Vitro Study
    · Journal of Food Biochemistry · 2026
    Source →
  2. [2]
    Effects of GABA-enriched rice germ extract fermented by Lactobacillus brevis BJ20 on stress symptoms and related biomarkers in adults: a randomized, double-blind, placebo-controlled trial
    · Journal of Functional Foods · 2026
    Source →
  3. [3]
    Levilactobacillus brevis CD2 as a multifaceted probiotic to preserve oral health: results of a double-blind, randomized, placebo-controlled trial in healthy adults
    · Journal of Translational Medicine · 2025
    PMID 39875908 →
  4. [4]
    The Probiotic Effects of Lactobacillus brevis CD2 on Caries Related Variables of Dental Plaque Biofilm
    · International Dental Journal · 2025
    PMID 40147282 →
  5. [5]
    Supplementation with Lactiplantibacillus brevis GKEX Combined with Resistance Exercise Training Improves Muscle Mass, Strength Performance, and Body Fat Condition in Healthy Humans
    · Foods · 2024
    PMID 38611334 →
  6. [6]
    Supplementation with a Probiotic Formula Having β-Glucuronidase Activity Modulates Serum Estrogen Levels in Healthy Peri- and Postmenopausal Women
    · Journal of Medicinal Food · 2024
    PMID 38742994 →
  7. [7]
    Effect of Chocolate Containing Lactobacillus brevis NTT001 and Galactooligosaccharides on the Intestine: A Randomized, Placebo-Controlled, Double-Blind Crossover Trial
    Lactobacillus brevis NTT001 およびガラクトオリゴ糖含有チョコレートの腸に対する影響―ランダム化プラセボ対照二重盲検クロスオーバー試験―
    · 薬理と治療 · 2021
    Source →
  8. [8]
    Effect of Chocolate Containing Lactobacillus brevis NTT001 and Galactooligosaccharides on the Intestine: A Randomized, Placebo-Controlled, Double-Blind Crossover Trial
    Lactobacillus brevis NTT001およびガラクトオリゴ糖含有チョコレートの腸に対する影響-ランダム化プラセボ対照二重盲検クロスオーバー試験-
    · 薬理と治療 · 2021
    Source →
  9. [9]
    Lactobacillus brevis CD2 attenuates traumatic oral lesions induced by fixed orthodontic appliance: A randomized phase 2 trial
    · Orthodontics and Craniofacial Research · 2020
    PMID 33259688 →
  10. [10]
    Relation between cell‐bound exopolysaccharide production via plasmid‐encoded genes and rugose colony morphology in the probiotic Lactobacillus brevis KB290
    · Animal Science Journal · 2019
    PMID 31593351 →