Strain Profile · NCBI Species Taxon 1584
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Lactobacillus delbrueckii

◐ Food-origin
Sequenced
Public genome assembly available

Lactobacillus delbrueckii is a lactic acid bacterium widely used in yogurt fermentation and industrial applications. The species comprises several subspecies (delbrueckii, bulgaricus, and lactis). Research has examined mechanisms of lactic acid production, fermentation characteristics, and viability in food matrices, as well as in vitro studies on antioxidative peptide production and physiological properties. Limited clinical research has investigated potential antifungal effects in animal models. The strain is primarily studied in fermentation science and food microbiology contexts.

Where it's been studied

Share of this strain's 225 body-system-tagged papers that concern each system. Research coverage, not measured effect.

+6 more systems

Symptoms in the research

Share of this strain's 85 symptom-tagged papers that mention each symptom or condition. Research coverage, not evidence of benefit.

+11 more symptoms

Research

930 papers reference this strain in the probiotic database.

Match confidence
2026 REVIEW
Lactobacillus delbrueckii: A Functional Powerhouse in Dairy Fermentation and Emerging Probiotic Applications
· Food Science & Nutrition
2026 OBSERVATIONAL
Viability of Lactobacillus delbrueckii subsp. bulgaricus in commercial yogurt products sold in North Carolina
· Discover Food
2025 OBSERVATIONAL
Lactobacillus delbrueckii subsp. allosunkii and lactis as emerging human uropathogens in elderly patients
· Journal of Clinical Microbiology
2025 WGS
A New Multilocus Sequence Typing Scheme for Lactobacillus delbrueckii subsp. bulgaricus Based on Whole-Genome Sequencing Data
· Current Microbiology
2025 WGS
Multi-omics research reveals the genetic characteristics and acid resistance mechanism of Lactobacillus delbrueckii subsp. lactis DB-8 screening from Xizang fermented dairy
· Food Bioscience
2025 OTHER
A Novel Peptide Derived from Casein Hydrolysates as a Growth Factor for Lactobacillus delbrueckii subsp. bulgaricus sp1.1
· Applied Biochemistry and Biotechnology
2025 IN_VITRO
Highly active β-galactosidase from Lactobacillus delbrueckii for enhanced lactose-derived oligosaccharide synthesis
· LWT
2025 IN_VITRO
Auto-aggregation Properties of Probiotic Lactobacillus delbrueckii str. IAHAHI: From Genes to Function
· Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca Food Science and Technology
2025 OTHER
Lactobacillus delbrueckii Alleviate Oxidative Stress and Intestinal Injuries by Activating TLR2 and TLR4 Expressions in IPEC-J2 Cells
· Probiotics and Antimicrobial Proteins
2025 OTHER
Engineering the D-lactic acid responsive promoter/repressor system as dynamic metabolic engineering tool in Lactobacillus delbrueckii subsp. bulgaricus for controlled D-lactic acid biosynthesis
· Enzyme and Microbial Technology
2025 OTHER
Metabolites from Lactobacillus delbrueckii subsp. bulgaricus DLPU F-36 and L-Arginine promote immune tolerance to whey protein in rats by modulating Th1/Th2 and Th17/Treg balance
· Food Bioscience
2025 IN_VITRO
Stress resistance of the biofilm and planktonic forms of Lactobacillus delbrueckii in adverse environments
· Letters in Applied Microbiology
2025 OTHER
Tailoring the physico-chemical properties and VOCs of pea-based fermented beverages through Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus fermentation
· Food Research International
2025 OTHER
Gut microbiota and immune regulation by Lactobacillus delbrueckii subsp. bulgaricus LB42: From preclinical safety assessment to clinical evidence
· Food and Chemical Toxicology
2025 IN_VITRO
Beneficial Effects of Lactobacillus delbrueckii subsp. lactis N102 and Lactobacillus sakei H1-5 Added as Starter Strains on the Metabolome, Safety and Quality of Dry-Fermented Sausages
· Foods
2025 ANIMAL
Modulation of Gut Microbial Composition by Lactobacillus delbrueckii subsp. lactis CKDB001 Supplementation in a High-Fat-Diet-Induced Obese Mice
· Nutrients
2025 IN_VITRO
The Impacts of Lactobacillus delbrueckii and Lactobacillus rhamnosus to Promote In Vitro Anti‐Inflammatory Profile of RA‐Macrophages
· Food Science & Nutrition
2025 RCT
Efficacy and Safety of Lactobacillus delbrueckii subsp. lactis CKDB001 Supplementation on Cognitive Function in Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
· Nutrients
2025 IN_VITRO
EFFECT OF B VITAMIN ADDITION ON THE BIOSYNTHESIS OF LACTIC ACID BY LACTOBACILLUS DELBRUECKII
· Biotechnologia Acta
2025 OTHER
A novel Lactobacillus delbrueckii-based topical spray promotes wound healing and inhibits dermal fibrosis: A probiotic biomaterial for integrated scar management
· Chemical Engineering Journal
Browse all 930 papers →

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Citations

Selected papers that name this strain.

  1. [1]
    Lactobacillus delbrueckii: A Functional Powerhouse in Dairy Fermentation and Emerging Probiotic Applications
    · Food Science & Nutrition · 2026
    PMID 41710811 →
  2. [2]
    Efficacy and Safety of Lactobacillus delbrueckii subsp. lactis CKDB001 Supplementation on Cognitive Function in Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
    · Nutrients · 2025
    PMID 41156564 →
  3. [3]
    Postbiotics from Lactobacillus delbrueckii Alleviate Intestinal Inflammation by Promoting the Expansion of Intestinal Stem Cells in S. Typhimurium-Induced Mice
    · Foods · 2024
    PMID 38540864 →
  4. [4]
    Health-promoting effects and safety aspects of Lactobacillus delbrueckii: A food industry species
    · Trends in Food Science & Technology · 2024
    Source →
  5. [5]
    The Efficacy of Lactobacillus delbrueckii ssp. bulgaricus Supplementation in Managing Body Weight and Blood Lipids of People with Overweight: A Randomized Pilot Trial
    · Metabolites · 2024
    PMID 38393021 →
  6. [6]
    Effect of Lactobacillus delbrueckii subsp. lactis on vaginal radiotherapy for gynecological cancer
    · Scientific Reports · 2023
    PMID 37344615 →
  7. [7]
    Consumption of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 augments serum antibody titers against seasonal influenza vaccine in healthy adults
    · Bioscience of Microbiota Food and Health · 2022
    PMID 36660594 →
  8. [8]
    Probiogenomics of Lactobacillus delbrueckii subsp. lactis CIDCA 133: In Silico, In Vitro, and In Vivo Approaches
    · Microorganisms · 2021
    PMID 33919849 →
  9. [9]
    Lactobacillus delbrueckii Ameliorates Intestinal Integrity and Antioxidant Ability in Weaned Piglets after a Lipopolysaccharide Challenge
    · Oxidative Medicine and Cellular Longevity · 2020
    PMID 32104535 →
  10. [10]
    Effect of ingesting yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on influenza virus-bound salivary IgA in elderly residents of nursing homes: a randomized controlled trial
    · Acta Odontologica Scandinavica · 2019
    PMID 31094267 →